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What provides the building blocks for synthesizing all neurotransmitters?


A) substances found in the diet
B) breakdown products of DNA
C) breakdown products formed from other transmitters
D) methane and ethanol

E) C) and D)
F) B) and D)

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LSD and other hallucinogenic drugs probably exert their effects most directly on what part of the neuron?


A) the axon terminals
B) the postsynaptic receptors
C) the reuptake protein channels
D) the sodium-potassium pump

E) B) and C)
F) A) and D)

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With respect to drug effects, "efficacy" means the tendency of a drug to:


A) have inhibitory effects.
B) have excitatory effects.
C) attach to a receptor.
D) activate a receptor.

E) None of the above
F) C) and D)

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At high doses, MDMA:


A) destroys axons that release acetylcholine.
B) destroys axons that release serotonin.
C) stimulates axons that release acetylcholine.
D) destroys axons in humans, but not in laboratory rats.

E) B) and C)
F) A) and B)

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The anterior pituitary is composed of:


A) glandular tissue.
B) neural tissue.
C) vaso tissue.
D) lymph tissue.

E) B) and D)
F) None of the above

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High concentrations of all neurotransmitters, except for NO, are stored in the:


A) presynaptic terminals.
B) postsynaptic terminals.
C) axon.
D) cell body.

E) All of the above
F) B) and C)

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At the synapse, amphetamine:


A) blocks the breakdown of dopamine.
B) increases the release of dopamine from the presynaptic terminal.
C) increases the sensitivity of dopamine receptors.
D) decreases the sensitivity of dopamine receptors.

E) B) and C)
F) A) and B)

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Increased permeability to ____ would most likely result in an IPSP.


A) sodium
B) potassium
C) calcium
D) bicarbonate

E) None of the above
F) A) and B)

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A common drug to treat alcoholism that produces illness after consuming alcohol is:


A) antabuse
B) NMDA
C) COMT
D) anandamide

E) None of the above
F) B) and C)

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Avoiding foods with lecithin, such as eggs and peanuts, would affect which neurotransmitter level the most?


A) acetylcholine
B) serotonin
C) GABA
D) endorphin

E) B) and C)
F) B) and D)

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Which neurotransmitter has been repeatedly connected with addictive drugs?


A) epinephrine
B) acetylcholine
C) serotonin
D) dopamine

E) B) and C)
F) A) and D)

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Which of the following neurotransmitters is released by active neurons to dilate the blood vessels and increase blood flow?


A) endorphins
B) glycine
C) nitric oxide
D) acetylcholine

E) B) and C)
F) A) and C)

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A drug that mimics or increases the effects of a neurotransmitter is called a(n) :


A) agonist.
B) antagonist.
C) stimulant.
D) protagonist.

E) A) and B)
F) B) and C)

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When a vertebrate animal contracts the flexor muscles of a leg, it relaxes the extensor muscles of the same leg. Sherrington considered this evidence for the existence of:


A) spatial summation.
B) temporal summation.
C) inhibitory messages.
D) the delay in transmission at synapses.

E) B) and C)
F) A) and D)

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Briefly compare the differences between ionotropic and metabotropic receptors. Include their mechanisms of action and how this explains the difference in their effects on the postsynaptic cell.

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Ionotropic receptors are ion channels th...

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What effect do opiate drugs have on dopamine?


A) They increase the synthesis of dopamine.
B) They directly increase the release of dopamine.
C) They indirectly increase the release of dopamine by blocking transmitters that normally block dopamine.
D) They mimic dopamine.

E) All of the above
F) B) and C)

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A certain drug user experiences intensified sensations and the illusion that time is passing slowly. He also experiences problems with attention and memory. These symptoms are most characteristic of the use of which drug?


A) LSD
B) cocaine
C) nicotine
D) marijuana

E) None of the above
F) All of the above

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Why do the effects of certain transmitters, such as serotonin, vary from one synapse to another?


A) The brain releases different forms of serotonin at different synapses.
B) It depends whether it is an original serotonin molecule or one that has been recycled.
C) The width of the synaptic cleft varies from one synapse to another.
D) There are several kinds of postsynaptic receptors for serotonin.

E) A) and B)
F) A) and C)

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What makes nitric oxide unique among neurotransmitters?


A) It is released before the action potential occurs.
B) It is taken back up into the presynaptic neuron.
C) It is a gas.
D) It is composed of amino acids.

E) B) and C)
F) B) and D)

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Compared to ionotropic effects, metabotropic effects are:


A) quicker and briefer.
B) slower and briefer.
C) quicker and longer-lasting.
D) slower and longer-lasting.

E) A) and D)
F) All of the above

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