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When EcoRI recognizes the sequence G-A-A-T-T-C it cuts a strand between the G and A on the double strand.What is the sequence of the sticky end on one of the strands of the DNA strand shown? 5' 3' -G-A-A-T-T-C- -C-T-T-A-A-G- 3' 5'


A) -C-T-T-A-A
B) A-A-T-T-C-
C) G-A-A-T-C
D) Both A and B are correct.
E) All of these are correct.

F) C) and E)
G) A) and D)

Correct Answer

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All of the following terms are associated with recombinant DNA except


A) plasmids.
B) restriction enzymes.
C) bacterial cells.
D) ribonuclease.
E) sticky ends.

F) A) and E)
G) B) and E)

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The use of DNA testing to determine which antibiotic will have the fewest side effects in a particular individual would be classified as


A) genetic engineering.
B) bioinformatics.
C) gene therapy.
D) bioethics.
E) pharmacogenetics.

F) C) and D)
G) A) and D)

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E

All of the following terms are associated with recombinant DNA except


A) plasmids.
B) bacterial cells.
C) endonuclease.
D) hydrogen bonding.
E) restriction enzymes.

F) D) and E)
G) A) and B)

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A genetic map is a(an)


A) complex of DNA and histones formed in a cell nucleus before cell division.
B) segment of DNA that directs synthesis of a specific peptide or protein.
C) list of locations of markers that relate to inheritable traits.
D) set of identical copies of DNA segments from a single ancestor.
E) ordered list of the nucleotides in a segment of DNA.

F) None of the above
G) C) and D)

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C

When a specific sequence on a DNA strand is cut by a restriction endonulease this results in what is termed a(n)


A) blunt end.
B) sticky end.
C) termination.
D) ligated end.
E) None of these.

F) B) and D)
G) A) and B)

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B

Genomics is the study of


A) errors in the replication of DNA.
B) diseases whose transmission and occurrence are linked to heredity.
C) the characteristics and functions of complete sets of genes.
D) transference of genetic material from one species to another.
E) the science of using biological materials for economic advantage.

F) A) and B)
G) None of the above

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One type of hereditary mutation that results in a defect in the enzyme hexosaminidase A and causes mental retardation is called


A) albinism.
B) Tay-Sachs disease.
C) phenylketonuria.
D) muscular dystrophy.
E) prions disease.

F) A) and C)
G) A) and B)

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Telomerase is a(an)


A) constriction that determine the shape of chromosomes during cell division.
B) sequence of nucleotides that code for proteins which function as enzymes.
C) sequence of nucleotides that code for proteins which function as chemical messengers,usually hormones or neurotransmitters.
D) enzyme which adds specific groups of nucleic acids to the ends of the DNA molecule.
E) sequence of non-coding nucleotides at the ends of chromosomes.

F) A) and C)
G) A) and E)

Correct Answer

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A technique that sorts amino acids or DNA fragments on the basis of their size is


A) polymerase chain reaction.
B) recombinant DNA.
C) genetic selection.
D) electrophoresis.
E) mutation.

F) B) and C)
G) C) and D)

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The molecular basis of a mutation is most closely linked to a


A) defect in the transcription of a genetic message to mRNA.
B) change in the sequence of bases on a DNA molecule.
C) defect in the rRNA of ribosomes.
D) misplaced stop codon.
E) All statements are incorrect.

F) B) and E)
G) B) and D)

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A gene is a(an)


A) complex of DNA and histones formed in a cell nucleus before cell division.
B) segment of DNA that directs synthesis of a specific peptide or protein.
C) list of locations of markers that relate to inheritable traits.
D) set of identical copies of DNA segments from a single ancestor.
E) ordered list of the nucleotides in a segment of DNA.

F) All of the above
G) A) and B)

Correct Answer

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Circular strands of DNA located in the cytoplasm of bacterial cells are called


A) plastids.
B) plasmids.
C) palindromes.
D) chromosomes.
E) primer.

F) A) and E)
G) A) and B)

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The order of views of a genome map,from largest scale to smallest scale is


A) chromosome,physical map,genetic map,overlapping clones,nucleotide sequence.
B) nucleotide sequence,physical map,overlapping clones,genetic map,chromosome.
C) physical map,genetic map,chromosome,overlapping clones,nucleotide sequence.
D) chromosome,genetic map,physical map,overlapping clones,nucleotide sequence.
E) nucleotide sequence,chromosome,overlapping clones,physical map,genetic map.

F) A) and B)
G) A) and E)

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One type of hereditary mutation that results in a defect in the enzyme tyrosinase that causes a loss of skin pigment is called


A) albinism.
B) Tay-Sachs disease.
C) phenylketonuria.
D) muscular dystrophy.
E) prions disease.

F) A) and E)
G) B) and E)

Correct Answer

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A gene mutation that involves a change of one base in the DNA is called a ________ mutation


A) missense
B) frameshift
C) point
D) nonsense

E) B) and C)
F) All of the above

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The removal of a gene from one organism and incorporating it into the DNA of another is called


A) polymerase chain reaction.
B) recombinant DNA.
C) genetic selection.
D) electrophoresis.
E) mutation.

F) A) and B)
G) A) and C)

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Which of the following is a coding portion of DNA?


A) exon
B) centromere
C) intron
D) telomere
E) none of the above

F) A) and D)
G) C) and D)

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The portion of a DNA molecule that does not code for proteins is called a(an)


A) intron.
B) exon.
C) sticky end.
D) codon.
E) primer.

F) A) and D)
G) D) and E)

Correct Answer

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Telomeres are


A) constrictions that determine the shape of chromosomes during cell division.
B) sequences of nucleotides that code for proteins which function as enzymes.
C) sequences of nucleotides that code for proteins which function as chemical messengers,usually hormones or neurotransmitters.
D) enzymes which add specific groups of nucleic acids to the ends of the DNA molecule.
E) sequences of non-coding nucleotides at the ends of chromosomes.

F) A) and B)
G) A) and C)

Correct Answer

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